Please Sign the “Declaration of Cognitive Interdependence”
The Birth of a Declaration
On the very first TruNeura Mastermind of the year, Dr. Kristine Burke walked us through the newly released preprint, now publicly available, of what is, to our knowledge, the first randomized controlled trial of a precision medicine approach for Alzheimer’s disease. Not case reports. Not anecdotes. An RCT.
The outcomes were remarkable.
You’ve heard me talk about some of these before, but seeing them laid out, patient by patient, trajectory by trajectory, was different. These were people who had been told there was nothing to be done. People who were expected to decline. And yet… they didn’t.
They improved.
As a community, we began asking the obvious next question: How do we share this?
Some practitioners talked about writing to local senior living centers. Others wanted to reach out to neurologists, primary care doctors, or functional medicine colleagues who don’t currently treat cognitive decline. Everyone felt the same urgency, but we weren’t yet aligned on the form.
Then Dr. Ryan Arnold of Clava Health said something that changed everything:
“I wish instead of writing an letter signed by me, we had something signed by all of us. Something like the Declaration of Independence but for this moment in brain health.”
There was a pause.
And in that pause, I knew he was right.
I typed into the chat: That’s a really great idea.
An hour after the Mastermind ended, I opened a blank document and started writing.
That document, shaped and refined by this community, has now become what we are calling The Declaration of Cognitive Interdependence.
We welcome you, as a reader of our blog, to read it and sign it if it feels resonant.




